Biography
Dr. Pedro A. Jose is Professor of Medicine and Pharmacology/Physiology, The George Washington University School of Medicine & Health Sciences, Visiting Professor, Third Military Medical University, Chongqing, China, Visiting Professor, Anhui Institute of Cardiovascular Disease, Anhui, China, and Concurrent Professor, Nanjing University School of Medicine, Nanjing, China. The primary goal of Dr. Jose’s research is to determine the genetic and pharmacogenetic bases of human essential hypertension and the metabolic syndrome. Specifically, the mission of his laboratory is to study the role of dopamine, adrenergic, and angiotensin receptor subtypes and dopamine regulatory genes (e.g., G protein-coupled receptor kinase 4 [GRK4], sorting nexins, gastrin) on sodium transport in specific nephron segments and their roles in the pathogenesis and treatment of genetic hypertension and metabolic syndrome. Dr. Jose’s studies are performed in vitro and in vivo, using molecular and cell biological methods, including gene silencing, gene rescue (e.g., AAV vectors), confocal microscopy and biophysical imaging, and integrated physiology in rats, mice, and humans. A key finding of Dr. Jose’s research is the demonstration of the crucial role of gene variants of GRK4 in the pathogenesis and personalized treatment of hypertension. Dr. Jose and his associates have discovered genes that cause high blood pressure when sodium intake is excessive and more importantly, genes that cause high blood pressure when sodium intake is too low. He has published more than 380 scientific articles in book chapters and journals. His articles are currently cited more than 10,000 times, with 57 cited 50 or more times, 19 of which are cited more than 100 times. Four of his articles are covers of scientific journals, six are the subject of editorial commentaries, and two are featured articles. His Hirsch-index is 52. Dr. Jose has received several academic and research awards, including the 2003 Lewis K. Dahl Memorial Lecture (American Heart Association), 2007 Ernest H. Starling Distinguished Lecture (American Physiological Society), 2007 MERIT award (National Institutes of Health), and 2015 Excellence Award for Hypertension Research (American Heart Association).
Research Interest
Metabolic syndrome, Pharmacology, Health Sciences.
Biography
Jie Shen M.D., Investigator, Chief Physician Department of (1 ) Endocrinology and Metabolism (2 ) The center of immunological genetics and HLA typing, The First Affiliated Hospital of Nanjing Medical University Academic Position 1. Academic Committee Member for Chinese Diabetes Society Jiangsu Branch 2. Vice chairman for China Microcirculation Society Jiangsu Branch 3. Member of Expert Committee for China Marrow Donor Program 4. Academic Committee Member for China Diabetes and Microcirculation Society 5. Clinical Consultant for UpToDate. 6. Advisory Board Member for Medical Education Culture and Health Committee for the China Revolutionary Committee of the Kuomintang Jiangsu Branch EDUCATION & LISCENSE 6/2014- Ph. Doctor Candidate in Medical Sciences 11/2007-11/2008 Postdoctoral Fellow for NIH, NIDDK , Phoenix USA 12/2001-present Licensed to practice medicine in China 07/2000 M.D. and M.S. in Medical Sciences, Ningxia Medical College, Yinchuan, China (09/1997-07/2000) 07/1986 Graduated from Nanjing Medical University, major in Basic and Experimental Medicine, Nanjing , China (09/1982- 07/1986) Work Experience: 2009-Present : (1 ) Investigator, Chief Physician ,Director, The center of immunological genetics and HLA typing (CDMP data bank lab for Jiangsu Province), (2 ) Investigator, Chief Physician for the Department of Endocrinology and Metabolism, Jiangsu Province Hospital(First Affiliated Hospital of Nanjing Medical University) 2007- 2008 : Postdoctoral Fellowship at the Phoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, in Phoenix, Arizona. 2006-2009: Associate Investigator, Associate Physician, Associate Director, Clinical Scientific Research Center, Jiangsu Province Hospital(First Affiliated Hospital of Nanjing Medical University). 2002-2006: Associate Investigator, Acting Associate Director, HLA genotyping laboratory, Jiangsu Province Hospital(First Affiliated Hospital of Nanjing Medical University) 2001-2003: Physician-in-charge, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1997-2002: Assistant Investigator, Secretary of Scientific Research, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1995-1997: Technician-in-charge, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1989-1995: Technician, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1986-1989: Practice Technician, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University Research Experience: 2009-Present: Research for Epigenetic Regulation on Obesity and Type 2 Diabetes. Epidemiology Study on Chinese Population HLA Typing and HLA Related Diseases Research ( such as Type 1 Diabetes Subacute Thyroiditis and Thyroid Nodule) Clinical Practice on Endocrine and Metabolic Diseases 2007- 2008 : Postdoctoral Fellowship at the Phoenix Epidemiology and Clinical Research Branch, NIDDK, NIH, in Phoenix, Arizona. The major goal of my research in NIH is to identify the specific role of genetic factors in the etiology of diabetes. This work involves various methods of high throughput genotyping, use of techniques from population genetics and computational statistics to analyze genetic variation in humans. 2006-2009: Co-Investigator, Associate Director, Clinical Scientific Research Center, Jiangsu Province Hospital. 2002-2006: Co-Investigator, Associate Director, HLA genotyping laboratory, Jiangsu Province Hospital 2001-Present: Attending Physician, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1997-2002: Research Associate, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1995-1997: Research Assistant, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1989-1995: Technician, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1986-1989: Practice technician, Department of Endocrinology, The First Affiliated Hospital of Nanjing Medical University 1990-1993: Scientific Research Co-operation, Institute of Genetics, School of Life Science , Fudan University. Shanghi, China. 1995-1996: Scientific Research Co-operation, Institute of Biochemistry, Chinese Academy of Sciences. Shanghi, China. 2003-present: Scientific Research Co-operation, Institute of Genomic, Chinese Academy of Sciences. PROFESSIONAL AWARDS 1. Outstanding Scientist for Jiangsu Province 2007. The Organization of Awarding the Prize: The Government of Jiangsu Province 2. The Pathological Study of Macrovascular Disease in Type 2 Diabetic Patients. Rank of Award:â…£ Date of Issue: Nov.1995 Certificate No. : 4-144-2 The Organization of Awarding the Prize: Academic Committee of Science and Technology Prize Jiangsu Province , China. 3. The Study on Insulin Receptor Gene Variations and Their Relation With Insulin Resistance. Rank of Award:â…¢ Date of Issue: Dec.2001 Certificate No. : 3-231-1 The Organization of Awarding the Prize: Academic Committee of Science and Technology Prize Jiangsu Province , China. 4. The Study of Early Diagnosis and Prevention of Type 1 Diabetes Mellitus Rank of Award:â…¢ Date of Issue: Dec.2001 Certificate No. : 3-230-5 The Organization of Awarding the Prize: Academic Committee of Science and Technology Prize Jiangsu Province , China. 5. The Study of Risk Factors and its Pathology in Type 2 Diabets and its Macrovascular Complications Rank of Award:â…¢ Date of Issue: Dec.2003 Certificate No. : 3-166-2 The Organization of Awarding the Prize: Academic Committee of Science and Technology Prize Jiangsu Province , China. 6. The Cytomorphological Changes of Smooth Muscle Cell in Various Concentrations of Glucose. Awarded for the Excellent Article The Organization of Awarding the Prize: Academic Committee of Science and Technology Prize , Jiangsu Province , China. 7. The Pathological Study of Glucose Transport Gene on Type 2 Diabetes Mellitus Rank of Award:â…£ Date of Issue: Nov.1995 Certificate No. : 4-145-4 The Organization of Awarding the Prize: Academic Committee of Science and Technology Prize Jiangsu Province , China.
Research Interest
Endocrinology and Metabolism,immunological genetics,immunological genetics,Obesity .
Biography
Dimitris T. Papadimitriou received his MD, his PhD on Pediatric Endocrinology and his specialty on Pediatrics at the University of Patras, Greece. He subsequently received a master in pediatric endocrinology from the Paris V University, and a master in Medical Pedagogy at Joseph-Fourier University (Grenoble, France), where he worked as a Lecturer (CCU) for 2 years. Since December 2005 he is Director of the Department of Pediatric-Adolescent Endocrinology and Diabetes of the Athens Pediatric Center in Athens and a Scientific Associate - University Scholar of the 3rd Pediatric Clinic of the University of Athens at Attikon Hospital.
Research Interest
Pediatric Endocrinology & Diabetes